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Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

2 August 2021

INCIDENCE AND EPIDEMIOLOGY Anal cancer is a rare disease that accounts for <1% and <3% of all new cancer diagnoses and gastrointestinal tumours, respectively. The most common histological subtype is squamous-cell carcinoma of the anus (SCCA) with an annual incidence of 0.5-2.0 in 100 000.1

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